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Constantinos Simopoulos Selected Research

Mesna (Coenzyme M)

3/2009Mesna protects splanchnic organs from oxidative stress induced by pneumoperitoneum.
2/2008Prophylaxis with mesna prevents oxidative stress induced by ischemia reperfusion in the intestine via inhibition of nuclear factor-kappaB activation.
8/2006Mesna protects intestinal mucosa from ischemia/reperfusion injury.
9/2004Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner.
11/2003Effects of subchronic ifosfamide-mesna treatment on testes and semen characteristics in the rabbit.

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Constantinos Simopoulos Research Topics

Disease

17Neoplasms (Cancer)
05/2019 - 05/2002
8Ischemia
01/2021 - 08/2006
8Neoplasm Metastasis (Metastasis)
07/2013 - 01/2002
7Pancreatitis
01/2021 - 07/2013
6Reperfusion Injury
01/2021 - 08/2006
5Carcinoma (Carcinomatosis)
05/2019 - 01/2008
5Body Weight (Weight, Body)
01/2013 - 03/2003
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 05/2003
3Pneumoperitoneum
04/2016 - 03/2009
3Hypoxia (Hypoxemia)
04/2016 - 08/2002
3Necrosis
07/2013 - 05/2008
3Colorectal Neoplasms (Colorectal Cancer)
06/2012 - 05/2002
3Cholecystitis
10/2009 - 04/2008
3Adenocarcinoma
09/2008 - 01/2002
3Wounds and Injuries (Trauma)
09/2008 - 03/2008
3Stomach Neoplasms (Stomach Cancer)
01/2008 - 07/2002
2Liver Neoplasms (Liver Cancer)
06/2021 - 02/2014
2Acute Necrotizing Pancreatitis
07/2019 - 04/2014
2Melanoma (Melanoma, Malignant)
05/2019 - 12/2016
2Inflammation (Inflammations)
06/2016 - 06/2010
2Propofol Infusion Syndrome
06/2011 - 07/2007
2Cysts
01/2011 - 06/2005
2Fistula
01/2011 - 01/2004
2Cholelithiasis
10/2009 - 04/2008
2Acute Cholecystitis
10/2009 - 04/2007
2Critical Illness (Critically Ill)
09/2008 - 08/2006
2Obesity
04/2007 - 02/2005
1Hyperthermia
05/2019
1Liver Cirrhosis (Hepatic Cirrhosis)
10/2018
1Hepatitis
10/2018
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2016
1Lung Injury
06/2016
1Acute Lung Injury
06/2016
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2016
1Acute Kidney Injury (Acute Renal Failure)
01/2016
1Parathyroid Neoplasms (Parathyroid Neoplasm)
06/2014

Drug/Important Bio-Agent (IBA)

8salicylhydroxamic acid (SHAM)IBA
01/2021 - 02/2008
6ApigeninIBA
06/2021 - 07/2013
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2005 - 05/2002
5Mesna (Coenzyme M)FDA LinkGeneric
03/2009 - 11/2003
4Proteins (Proteins, Gene)FDA Link
04/2018 - 08/2002
4ImmunosorbentsIBA
11/2016 - 05/2002
4EnzymesIBA
11/2016 - 05/2002
4LeptinIBA
01/2013 - 01/2005
3Propofol (Diprivan)FDA LinkGeneric
06/2011 - 08/2006
3Thymidine PhosphorylaseIBA
04/2005 - 07/2002
2EugenolIBA
01/2021 - 01/2016
2Silybin (Lagosa)IBA
01/2021 - 11/2020
2Caspase 3 (Caspase-3)IBA
05/2019 - 04/2016
2AntioxidantsIBA
06/2016 - 03/2009
2Glutathione Disulfide (GSSG)FDA LinkGeneric
04/2016 - 06/2010
2Carbon DioxideIBA
04/2016 - 04/2005
2Fas Ligand Protein (Fas Ligand)IBA
04/2014 - 06/2012
2Cadherins (E-Cadherin)IBA
07/2013 - 01/2004
2Amifostine (Ethyol)FDA LinkGeneric
03/2011 - 09/2008
2CollagenIBA
01/2011 - 09/2008
2NF-kappa B (NF-kB)IBA
04/2009 - 02/2008
2Monoclonal AntibodiesIBA
03/2008 - 05/2002
2Sulfhydryl Compounds (Thiols)IBA
08/2006 - 09/2004
2IfosfamideFDA LinkGeneric
09/2004 - 03/2003
1Cisplatin (Platino)FDA LinkGeneric
06/2021
1FlavonoidsIBA
06/2021
1CyclodextrinsIBA
11/2020
1p21-Activated KinasesIBA
01/2019
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
10/2018
1Pemetrexed (MTA)FDA Link
04/2018
1isothiocyanic acidIBA
12/2016
1IsothiocyanatesIBA
12/2016
1SolventsIBA
11/2016
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
11/2016
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
11/2016
1Glutathione (Reduced Glutathione)IBA
04/2016
1GasesIBA
04/2016
1Caspase 8 (Caspase-8)IBA
04/2016
1CreatinineIBA
01/2016
1Interleukin-6 (Interleukin 6)IBA
01/2016
1Urea (Carbamide)FDA LinkGeneric
01/2016
1Interleukin-17 (Interleukin 17)IBA
12/2014
1C-Reactive ProteinIBA
12/2014
1technetium tc-99m tetrofosmin (Myoview)FDA Link
06/2014
1RadiopharmaceuticalsIBA
06/2014
1Radioisotopes (Radionuclides)IBA
06/2014
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
06/2014
1AmylasesFDA Link
04/2014
1Taurocholic Acid (Sodium Taurocholate)IBA
04/2014

Therapy/Procedure

8Laparoscopic Cholecystectomy
02/2014 - 01/2005
6Ligation
01/2021 - 11/2005
5Drug Therapy (Chemotherapy)
05/2019 - 11/2003
4Surgical Instruments (Clip)
04/2013 - 01/2008
3Laparotomy
07/2019 - 04/2008
3Artificial Respiration (Mechanical Ventilation)
06/2011 - 08/2006
2Operative Surgical Procedures
11/2016 - 01/2008
2Length of Stay
10/2009 - 04/2007
2Catheters
01/2004 - 01/2003
2Therapeutics
03/2003 - 05/2002
1Induced Hyperthermia (Thermotherapy)
05/2019
1Transplantation
10/2016
1Hepatectomy
10/2016
1Enteral Nutrition (Feeding, Tube)
06/2016
1Lymph Node Excision (Lymph Node Dissection)
01/2016